"It's the economy, stupid" is a slight variation of the phrase "The economy, stupid" which James Carville had coined as a campaign strategist of Bill Clinton's successful 1992 presidential campaign against sitting president George H. W. Bush. (Source: Wikipedia).
To understand PV-10 is to understand the relationship between chemoablation and immune-mediated signaling. It's what Craig means when he says the immune system responds in direct proportion to the degree of insult. Think of PV-10 chemoablation as the proxy for the degree of insult, which is rapid, complete and durable in the case of PV-10. Moffitt should say the same thing in its conference presentation(s) and contemporaneous peer-reviewed publication.
A good amount of work -- creative, innovative, pragmatic, historical, scientific, medical literature-based, etc. -- went and a continues to go into dosing, of historical and upcoming clinical trials, of certain indications, of pre-clinical work on newer indications.
Yes, management doesn't talk openly about dosing, nor do they talk openly about several other topics of import and value.