March 7, 2013

$PVCT: Simplifying Things

In designing PV-10, Craig's philosophy was and is to allow immune system to do the job mother nature intended it to do.

In addition to its robust safety, the drug has 3 unique characteristics that deeply matter to PV-10's proposition and make it so broadly efficacious:
  1. Delivery mechanism: Intra-tumoral injection,
  2. Multiple targeting: A full expression of antigens in context, and
  3. Tissue specificity: Destruction only of diseased tissue
Some context: PV-10's immunologic mechanism of action lies in a separate category than, say, Provenge. Provectus' drug triggers an internal vaccination (internal antigenization), while Provenge operates on the basis of an external vaccination (with very marginal efficacy).

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